Glossary

Glossary

Degronimid™

A DEGRONIMID™ is a small molecule that combines the ability to recruit a target protein of interest and the ubiquitination machinery.degronimid

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Proteasome

Proteasomes are protein complexes inside all eukaryotes and archaea, and in some bacteria. The main function of the proteasome is to degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds.
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Ubiquitin

Ubiquitin is a small protein that is found in almost all cells. It plays a central part in controlling the degradation and localization of proteins in the body.

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Targeted Protein Degradation

The ubiquitin-proteasome pathways play a major role in cellular protein destruction, and regulates the fundamental cellular processes, such as cell cycle, cell signalling, and development.degradation
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